POS0810 PULMONARY FINDINGS ON HIGH-RESOLUTION COMPUTED TOMOGRAPHY IN TAKAYASU ARTERITIS

Background: Takayasu arteritis (TA) is a chronic granulomatous large-vessel vasculitis most commonly seen in women under 50 years of age[1]. The pulmonary arteries are less often involved, with the frequency involvement varying widely between countries (from 4% to >50%) [2–5]. Respiratory symptoms or signs and imaging findings TA have not been fully investigated [6–7]. Objectives: This study aimed describe high-resolution computed tomography (HRCT) determine possible causes. Methods: A total 243 patients were enrolled from prospective cohort after excluding 260 other disorders incomplete data. Clinical data including symptoms, lab results, information collected. Pulmonary HRCT interpreted by two radiologist who blinded patients’ clinical information. Abnormal features recorded as nodules, stripe opacity (linear opacity), patchy opacity, ground-glass pleural thickening, effusion, infarction, mosaic attenuation, bronchiectasis, oedema. After evaluation, divided into groups: those normal lung abnormal HRCT. characteristics compared groups binary logistic regression analysis was applied identify potential risk factors for lesions. Follow-up (obtained 64 patients) analysed changes lesions at least 6 months’ treatment. Results: Of patients, 107 (44.0%) had while 136 (56.0%) HRCT, (60.3%), nodules (44.9%), (25.0%), thickening (15.4%), effusion (10.3%), (8.1%), infarction (6.6%), attenuation (4.4%), bronchiectasis (3.7%), oedema (2.2%). Patients significantly more likely type II arterial (25% vs. 12.2%, P = 0.04), (PAI; 21.3% 5.6%, < 0.001), hypertension (20.6% 8.4%, 0.01), heart function (27.9% 7.6%, 0.001). Logistic demonstrated that PAI (OR 3.0, 95% CI= 1.1-8.4, P=0.03), worsened 2.7, CI 1.1-6.6, age 1.1, 1.0-1.1, P<0.01) associated presence opacities improved partially Conclusion: rare TA. Age, PAI, References: [1]Jennette JC, Falk RJ, Bacon PA, et al. 2012 Revised International Chapel Hill Consensus Conference Nomenclature Vasculitides. Arthritis Rheum 2013;65:1-11. [2]Kong X, Ma L, Wu Evaluation measurements development new diagnostic criteria Chinese population. Clin Exp Rheumatol. 2015; 33(2 Suppl 89): S-48-55. [3]Nooshin D, Neda P, Shahdokht S, Ali J. Ten-year Investigation Clinical, Laboratory Radiologic Manifestations Complications Takayasu’s Arteritis Three University Hospitals. Malays J Med Sci. 2013; 20(3):44-50. [4]Bicakcigil M, Aksu K, Kamali Turkey – angiographic 248 patients. 2009; 27(1 52):S59-64. [5]Kechaou Frigui Ben Hmida Bahloul Z. Southern Tunisia 29 Presse Med. 38(10):1410-4. [6]Dou JB, Gong JN, ZH, Kuang TG, Yang YH. records diagnosed vascular involvement. Zhonghua Jie He Hu Xi Za Zhi. 2016; 39(8):603-7. [7]Nd Perera G, C Jayasinghe A, D Dias Kulatunga A. Bronchiectasis hoarseness voice takayasu arteritis: presentation. BMC Res Notes. 2012; 5:447. Disclosure Interests: None declared